Drugs that may cause erection problems: MedlinePlus Medical Encyclopedia

Regardless of the cause, the results can be devastating to relationships and the psyche.

When medication changes how one of these factors works—like blood pressure medication or depression medication—ED is a possible side effect. Asking your doctor for treatments for depression may help alleviate your erection problems as well. Often the inability to maintain an erection is due to a combination of conditions. Therefore, regardless of ED mechanism in hypertension, early diagnosis and correct approach of sexual life represent an important step of cardiovascular evaluation which certainly contributes for a better choice of hypertension treatment, preventing some complications and restoring the quality of life. Keep reading to learn more about this condition and how you can best manage it. Accordingly to these authors, possible reasons for the precocity of ED as clinical manifestation of systemic atherosclerosis were the small size of cavernosous arteries and the need of a huge dilation, nearly 80%, in penile circulation for an adequate blood supply for a full erection. So can I take Viagra with my heart medications?

  • When a man is sexually stimulated, a gas called nitric oxide (NO) is released and helps relax the muscles in the penis.
  • You might have an adverse reaction to a particular medication, or an alternative is unavailable in your state, health insurance plan, or your budget.
  • Medical advances apart, the best treatment for ED remain its prevention.
  • The waves fell, gently but quickly rushed to the coast, washing away the darkness under the hazy moonlight, and hissing backwards after rushing like a white snake, until silence, leaving only the pearly silver on the beach.

Endothelial dysfunction is considered one of the earlier steps of atherosclerosis process, preceding angiographic, ultrasonographic, and clinical evidences of vascular disease [66]. Often, a combination of physical and psychological factors contributes to erectile dysfunction. Don t ask what you can do, just give some suggestions, and do it directly if not offensive. Compared with carvedilol, long-term therapy with valsartan was significantly associated with improved sexual activity [6].

After 4 weeks (visits 3 and 7) of double-blind treatment with either nebivolol 5 mg once daily or metoprolol succinate 100 mg once daily subjects will be evaluated and the need for dosage titration assessed. In fact, some hypertension medicines may actually give a boost to a person's sex life. In a study designed to compare the effects of metoprolol and nebivolol in erectile tissue (MR-NOED), nebivolol was even shown to significantly improve erectile function of hypertensive patients due to nitric oxide modulation [26]. Don’t stop taking a medicine without first consulting your doctor.

In recent years, researchers have begun to understand that high blood pressure also takes a toll on female sexuality. Importantly, the heart conditions should be carefully clarified before initiation of medical treatment, as PDE5 inhibitors must not be used in certain cardiovascular conditions or at least require special precaution. These medications are classified as phosphodiesterase inhibitors and work by relaxing muscles in the penis, causing blood vessels to dilate and allowing increased blood flow, but only after appropriate physical and emotional sexual stimulation. Revatio is given to improve exercise ability and slow down worsening changes in people with this condition. In high risk subjects, cardiologic condition should be stabilized through medication, surgery, or other means before sexual rehabilitation. He fiddled with an ink absorber on the table frantically with his right hand. There are a number of prescription and over-the-counter drugs that may cause erectile dysfunction.

Find Out Which Drugs Might Have A Negative Effect On Your Sex Life

High blood pressure can reduce blood flow to the vagina. (03); however, the annual absolute increase in risk of withdrawal was only 2 per 1000 patients (95 % CI 0–5) [19]. Selective serotonin reuptake inhibitors (SSRIs) such as fluoxetine (Prozac), sertraline (Zoloft), and paroxetine (Paxil).

Talk with your doctor or other health care provider about the possibility of reducing dosage or switching to another antipsychotic drug. Healthy lifestyle choices include: 2% of placebo patients. In this sense, men knowledge about cardiovascular health and the relationship of ED with traditional risk factors should help physicians to motivate therapeutic adhesion and adoption of a healthier way of life [16].

Nonetheless, the incidence of sexual dysfunction associated with antipsychotic drugs ranges in different studies from 45 percent to as high as 90 percent.


Burchardt M et al. Studies with larger samples contradict small trials conclusions as they have not observed any association of ED and antihypertensive drugs, cholesterol levels, and even smoking [44]. Whether you're a man or a woman, high blood pressure can definitely put a damper on your sex life. Other conditions that may contribute to erectile dysfunction include Parkinson’s, multiple sclerosis, Peyronie’s disease, sleep disorders, smoking, alcoholism and drug abuse. Blood or plasma concentrations may be measured to confirm a diagnosis of overdose or poisoning in hospitalized patients or to assist in a medicolegal death investigation.

But psychological aspects of man sexuality interfere in all steps of sexual disorders and could complicate diagnostic attempts or harm therapy efforts. Serious side effects that are advised to be reported immediately include symptoms of bradycardia (resting heart rate slower than 60 beats per minute), persistent symptoms of dizziness, fainting and unusual fatigue, bluish discoloration of the fingers and toes, numbness/tingling/swelling of the hands or feet, sexual dysfunction, erectile dysfunction, hair loss, mental/mood changes, depression, breathing difficulty, cough, dyslipidemia and increased thirst. Group 1 (24 patients) who were taking 5 mg of nebivolol, Group 2 (28 patients) who took 100 mg of atenolol, Group 3 (29 patients) who were taking 10 mg of bisoprolol, and Group 4 (27 patients) who were on 25 mg of carvedilol. Any comments viagra and tinnitus or inquiries are directed to us, even if My mother was there, such as Does your mother want something to drink Nisha can provide useful advice every time, so that we don t have to encounter a little thing to trouble Dr. For some men, the decreased blood flow makes it difficult to achieve and maintain erections — often referred to as erectile dysfunction. In well controlled hypertensive subjects who take one or two antihypertensive drugs and have no other risk factors, indicating low cardiovascular risk, PDE5 inhibitors could be tried. Some over-the-counter antihistamines and decongestants can cause erectile dysfunction or problems with ejaculation.

Specifically, Viagra shouldn’t be used in combination with a nitrate drug for treating chest pain or heart problems.

The articles on Health Guide are underpinned by peer-reviewed research and information drawn from medical societies and governmental agencies. Kochar MS et al. ED isn’t a natural part of aging, but the risk of experiencing it does increase as men get older. Diuretics can decrease forceful blood flow to the penis, making it difficult to achieve an erection. Only a small percentage of cases of impotence are caused by hormone deficiency. Intracavernosous self-injection and penile prostheses constitute the most common path for men refractory to oral therapy [11]. Lemonaid’s ED service https: Because of this, metoprolol is always manufactured in a salt-based solution, as drugs with low melting points are difficult to work with in a manufacturing environment.

US National Library of Medicine.

Prostate Cancer And Erectile Dysfunction

This is called venous leakage. Can high blood pressure affect sexual functioning? Knowledge about sexuality seems important as men and women increased their life expectance and want to keep quality of life during aging. Articles and news (read all related articles.), initially try to set aside 10 minutes a few days a week for training. Two cylindrical tubes, called the corpus cavernosum, that run the length of the penis fill with this increased blood volume and cause the penis to stiffen, straighten, and become erect. In the same way, data with diuretics and ED are not conclusive. In fact, it’s estimated that more than 30 million American men have experienced erection problems (Nunes, 2020). If the patient experiences ED due to the propranolol, we can see if he experiences the same benefit from Topamax, which is also used to prevent migraines and isn’t generally associated with ED.

Impotence was mentioned in 10. Wheezing (bronchospasm), dyspnea. For many, erectile dysfunction or ED is an all-too-real concern. Likewise, Lamina et al. Probably the real impact of ED was even greater with a strong relationship with aging and some authors estimated that almost half of 70-year-old men live with some degree of ED [5, 6]. Meaning of ED as a cardiovascular risk marker.

Q: I have diabetes and a replaced valve. Will Viagra hurt my conditions?

Some men who have ED experience an unhappy sex life, loss of intimacy with partners, anxiety, and depression. Feeling of frustration, embarrassment, shame, and anxiety settle in, especially if the problem continues to go unresolved. Indeed, in the TOMHS trial, amlodipine did not appear to affect sexual function [30], neither did nicardipine [60], nifedipine or diltiazem in other studies [61, 62]. In all, 12 nonsmoking hypertensive men with erectile dysfunction, otherwise healthy, participated in the study, which was approved by the Ethics Committee of the University of Turku. No differences were seen between the use of ramipril, telmisartan or a combination of the two and there was no evidence for adverse effects of both treatments on erectile function [54]. One option doesn’t even require you to leave your own home to visit a doctor! Some people are able to do that through lifestyle changes alone.

Keep in mind that it can take anywhere from several days to several weeks after stopping a high blood pressure medication for erections to return. In several other vascular territories, NO participation on venous side of circulation is minimal or null [67]. On the other hand, statins have been reported to improve erectile function when the cohorts had no other cardiovascular risk factors accept for untreated ED [70–72].

α-adrenergic Antagonists

In the few studies concerning sexual function in female patients with antihypertensive treatment, metoprolol seems to negatively affect female sexual function index scores (FSFI) [16], especially in comparison with ARBs which seem to ameliorate FSFI scores [17, 18]. Agranulocytosis, nonthrombocytopenic purpura, thrombocytopenic purpura. Erections are extremely complicated and surprisingly fragile. That is not too surprising, since ED often occurs in men who smoke or are overweight—both of which are common risk factors for high blood pressure. PDE5 inhibitors, ED’s first line therapy, present a mechanism of action based on NO bioavailability. Nowadays, the more commonly used term is "erectile dysfunction". The following medications might contribute to ED:

In atherosclerosis, the arteries are clogged and narrowed, resulting in reduced blood flow. Kloner explained that cardiovascular disease and erectile dysfunction often go hand-in-hand. Co-located with the Shands Jacksonville Hospital, the Jacksonville Health Science Center excels in education, research and patient care that expresses our abiding values of compassion, excellence, professionalism and innovation. Smoking contributes to vascular disease (disease of the blood vessels), so it can contribute to erectile dysfunction by affecting blood flow to the penis.

Oral ED drugs help increase the effects of NO to assist men who have trouble getting or keeping an erection. Student's paired t-test for parametric data and the χ2 test for categorial data were used. NIH National Institutes of Health. Depending on the class of the antihypertensive drug and its effect over endothelium mediators, the impact on ED could be positive or negative. They found that vasodilation of the brachial artery by both mechanisms, endothelium-dependent and independent, was significantly compromised in the group suffering from ED, which illustrates that vascular alterations involved in ED are a generalized process [67]. Sleep disorders were also more prevalent among ED men and their treatment could help in recovering sexual satisfaction [32].

  • Also, let your healthcare provider know if you’ve been told not to have sex for health reasons before starting on Viagra.
  • Most men with hypothetic vasculogenic ED present at least one traditional cardiovascular risk factor [19].
  • At the end of the treatment phases, the subjects were asked about their subjective erectile capacity (nocturnal and coital erections).
  • The association of ED and vascular risk factors including hypertension raises the hypothesis that endothelial dysfunction is the common link between erectile dysfunction and cardiovascular disease.

See Also

Study data suggests it affects 18 million men over the age of 20 in the United States. The penile vascular velocities were measured before treatment and after a treatment phase of eight to twelve weeks of beta blocker antihypertensive treatment. Inflatable devices or malleable rods can be surgically implanted on either side of the penis to help achieve an erection. 6/31 one in five brits admit to having had an affair. The UFHSC-J is a clinical teaching site for the Gainesville-based College of Nursing.

Similarly, effects of sildenafil on blood pressure in hypertensive patients on multiple antihypertensive drugs were minimal and well tolerated [79, 80]. Erectile dysfunction may be an unpleasant condition that no one really wants to talk about, failing to acknowledge it won’t make the problem go away. Antidepressants and other psychiatric medicines:

Next Article

Here is an overview of each category: Due to this mechanism of action, calcium antagonists are not expected to cause sexual dysfunction [7]. Investigators found that in a group of 160 males (without a history of cardiovascular events), aged 40 to 49 years, who had been recently diagnosed with hypertension, carvedilol was associated with 15 reports of erectile dysfunction over a 16 week period, compared to one report of erectile dysfunction in patients taking valsartan (an angiotensin II receptor antagonist).

Benzodiazepines may also interfere with the production of testosterone, a hormone important for sexual desire in women as well as men. Over time, high blood pressure damages the lining of blood vessels and causes arteries to harden and narrow (atherosclerosis), limiting blood flow. The first step in the process is always to reevaluate if the medication that’s causing the problem is even necessary in the first place. These clinical manifestations rarely are symmetrical in the same patient, probably due to different sizes of arterial tree that irrigate territories such as penile, heart, brain, and legs [20], and different needs of blood supply and vasodilation of each structure [67]. A very common cause of impotence is when blood flow into the penis is reduced. The dosage may be increased to a maximum of Lopressor 450mg per day, if there is no therapeutic response, or if it is low. Even when patients return claiming nonresponse to PDE5 inhibitor, it is recommended to check all steps where medication were tried and review psychological conditions, partner collaboration, blood pressure control, glucose and cholesterol levels [83]. What is erectile dysfunction?


It's known that diuretics (or water pills, like hydrochlorothiazide) and beta-blockers (like Atenolol) can also cause erection problems. It undergoes α-hydroxylation and O-demethylation as a substrate of the cytochrome liver enzymes CYP2D6[29][30] and a small percentage by CYP3A4, resulting in inactive metabolites. According to the American Heart Association, most people with heart trouble can enjoy sex safely -- and that includes those with high blood pressure. This medicine is also sold under the name Revatio to treat adults with pulmonary arterial hypertension (high blood pressure in the lungs). He might also be unable to have a hard erection.

Obviously, you shouldn’t make this decision on your own and should instead have a simple conversation with your healthcare provider about it. Long-standing hypertension may cause oxidative stress, endothelial cell injury, and its consequences, including the inability of arteries, arterioles, and sinusoids of the corpus cavernosum to dilate properly [60]. How do hypertension medications affect sexuality? Risk factors for atherosclerosis include: As ED is highly prevalent and deeply impacts overall health of sexually active men, sexual function should be part of anamneses in all hypertensive subjects, especially those over 50 years. But what — exactly — happens?

Here's the good news: The TOMHS trial (The Treatment Of Mild Hypertension Study), a 4-year follow-up, double-blind RTC in 557 men and 345 women, showed that chlortalidone at a dose of 15 mg/day may also be suspected to negatively affect sexual function in men [30]. By making healthy lifestyle choices, you can lower your blood pressure and potentially improve your sex life. It would seem reasonable to manage these patients in the same way as those with heart failure with reduced ejection fraction (HF-REF), while noting that patients with HF-PEF may be more “brittle”. Use adequate PDE5 inhibitors dosage.

  • A recent systematic review on the effect of α1-adrenoceptor antagonists on male sexual function was performed by Van Dijk et al.
  • Certain exercises.
  • 89 in the placebo group, 5.
  • Recently, Chang et al.
  • Some authors state that ED symptoms in hypertensive patients would represent deterioration in endothelial dysfunction already present and should alert for a possible progression of a systemic vasculopathy [61].
  • Giving up smoking often has a beneficial effect on erectile function.
  • Diabetes contributes to ED by damaging your nerves and blood vessels.

Diagnosis of Male Pattern Baldness

What if we olmesartan side effects erectile dysfunction avoid talking and make our mother more lonely, depriving her of the opportunity to share fear and hope with us Moreover, her faith tells her Penis Enlargemenr Does Metoprolol Cause Erectile Dysfunction O. Come to rest, then vocational training, entertainment, dinner, go to bed at eight. Shopping cart, in addition, when research has shown a nutrient such as zinc or niacin to improve sexual function, it's usually in people who are deficient in it. 05 was considered statistically significant. Or, a combination of medications might work better to control high blood pressure and lower the risk of erectile dysfunction.

Medical Care

Nerve and artery damage can be caused by prolonged cycling, rodeo riding, or use of a rowing machine, resulting in the inability to get an erection. In addition, detailed recommendations for cardiovascular patients, concerned about a potential risk of sexual intercourse in the light of their underlying cardiovascular condition, are available both for further diagnostic workup and therapeutic interventions according to the first and second Princeton Consensus Conference [74, 77]. The sedative and muscle-relaxant properties of benzodiazepines are thought to lessen sexual interest, excitement and sensation. They showed that α-adrenergic antagonists used as treatment for hypertension do not seem to adversely affect sexual desire. Eccentric control contraction, (But don’t do this on a regular basis – this should only be done when trying to locate the correct muscles.). Another interesting aspect of ED knowledge in hypertensive subjects approach is that some evidences point out to an improvement in blood pressure control maybe as a consequence of better therapeutic compliance after PDE5 inhibitor therapy [82]. 9 million men. Cardiovascular disease is not a contraindication to sexual activity in patients who have been properly assessed and treated. The other piece of advice my friendly cardiologist gave me was post-MI, if they can walk up two flights of stairs Viagra was fine; again, not what I had been led to believe historically.

Try at least four to six times in different situations before giving up. In this way, search for new data on basic mechanism under ED development in hypertensive individuals is an actual need. An unexpected error has occurred. Some prescription medications and even over-the-counter drugs can have an impact on sexual functioning. It seemed that something steve harvey male enhancement products secret happened. Bystolic is taken orally. Men considering medications for erectile dysfunction should check with their doctor first. Top stories, looking for natural solutions to ED? When clinical failure with PDE5 inhibitor is confirmed, urologist should participate and evaluate possible options to allow an active and satisfactory sexual life.

The fact that ACE inhibitors work through other channels than the sympathetic nervous system in lowering blood pressure might in part explain their reduced impact on sexual function. This protocol is designed to compare the effects two beta blockers, nebivolol (Bystolic) 5-10 mg daily with metoprolol succinate (Toprol XL) 100-200 mg daily on sexual function in post-menopausal women with high blood pressure. The following medications may decrease sexual desire: However, as there appears to be a nocebo affect associated with the use of beta-blockers the act of switching a patient with erectile dysfunction from metoprolol to carvedilol, may produce therapeutic benefit.


What is sexual dysfunction? In general, patients with heart failure and erectile dysfunction can be successfully treated with PDE5-inhibitors and this may even correlate with an increase in exercise tolerance. Firstly, it is important to provide an adequate room to talk about sexual dysfunction. Some of the study participants were told about the sexual side effect of the blood pressure drug, and ED was reported by almost one-third of the participants.

UF Health at Gainesville

Heart disease, atherosclerosis, high cholesterol and high blood pressure can all impact the amount of blood flowing to the penis. 2% of men referring any degree of sexual dysfunction at inclusion. Flomax precautions, also, the effect of the medication improves the process of excretion of urine. Has your relationship with your sexual partner changed recently? What are the types of sexual dysfunction? Several studies showed that more than a half of ED men leave offices with prescription of PDE5 inhibitor but without correct information about its posology [83]. One of the proposed mechanisms by which β-blockers may induce sexual dysfunction is inhibition of the sympathetic nervous system, which is involved in the integration of erection, emission and ejaculation, in the regulation of luteinising hormone secretion and in the stimulation of testosterone release [10].

This is an important point since patient concerns about the adverse effects of drugs on erectile function might limit the use of essential medications in cardiovascular high-risk patients [43]. Metoprolol may worsen the symptoms of heart failure in some patients, who may experience chest pain or discomfort, dilated neck veins, extreme fatigue, irregular breathing, an irregular heartbeat, shortness of breath, swelling of the face, fingers, feet, or lower legs, weight gain, or wheezing. To detect if beta blockers have been used trace analysis of human urine is analyzed. Still, Viagra isn’t expected to cause harm during pregnancy. Often, minimising the use of hard bicycle seats and exercise machine seats, as well as correct positioning of the seat, will help restore sexual function. Why they’re prescribed: In many cases, ED is rooted in psychological issues — especially in men under 40 years of age. The mechanism of action is not completely understood.

Talk with your doctor about what you’re concerned about and discuss how you want to manage blood pressure. 58 in the bendroflumethiazide group. ” Talk with your doctor or other health care provider. An in vitro study demonstrated statin effects on human testicular testosterone synthesis [67] and in animals effects on the morphology and function of Leydig cells have been seen after statin administration [68].